Top Three Conditions Can Worsen IgA Nephropathy

Top Three Conditions Can Worsen IgA Nephropathy

Top Three Conditions Can Worsen IgA Nephropathy IgA Nephropathy is a kidney disease that causes the kidneys to become inflamed. Several conditions can induce its occurrence or worsen its conditions. So what are the leading factors of IgA Nephropathy.

First, what is IgA Nephropathy?

Immunoglobulin A Nephropathy is short for IgA Nephropathy. It is a common glomerular disease and it is characterized by IgA deposition. The major signs of IgA Nephropathy is blood in urine or protein in urine. When you have upper respiratory infection, hematuria or proteinuria relapse or become worse. Most patients with this disease have good prognosis, while only few patients will have decreased glomerular parenchymal cells and renal fibrosis of mesenchymal cells, which has a worse prognosis.

Second, what are leading factors worsening IgA Nephropathy?

Here we talk about three leading factors that can aggravate IgA Nephropathy. They are:

1. Infection

Infection can not only cause IgA Nephropathy but also can aggravate and induce IgA Nephropathy. The commonest infection is upper respiratory infection, which is usually virus infection. Other system infections like gastrointestinal infection and urinary tract infection are also inducing factors.

2. Vaccination

It may also induce and aggravate IgA Nephropathy.

3. Medium and massive proteinuria

Researches have shown that the degree of proteinuria is closely related to prognosis. When proteinuria is larger than 3g/d, the declined speed of kidney function is 25 times than patients with less than 1g/d proteinuria.